Base-editing mutagenesis maps alleles to tune human T cell functions.
Schmidt R, Ward CC, Dajani R, Armour-Garb Z, Ota M, Allain V, Hernandez R, Layeghi M, Xing G, Goudy L, Dorovskyi D, Wang C, Chen YY, Ye CJ, Shy BR, Gilbert LA, Eyquem J, Pritchard JK, Dodgson SE, Marson A
Nature. 2024 Jan;625(7996):805-812. doi: 10.1038/s41586-023-06835-6. Epub 2023 Dec 13.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 234041 | pLenti-CR029 | expresses evoCDA1 BE4max base editor in a human T cell optimized lentiviral transfer plasmid |
| 234042 | pLenti-CR033 | expresses ABE8e(V106W) base editor in a human T cell optimized lentiviral transfer plasmid |
| 234043 | pLenti-CR102 | expresses ABE8e(V106W) - SpG Cas9 base editor in a human T cell optimized lentiviral transfer plasmid |