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Overexpression screen of chromosome 21 genes reveals modulators of Sonic hedgehog signaling relevant to Down syndrome.

Moyer AJ, Fernandez FX, Li Y, Klinedinst DK, Florea LD, Kazuki Y, Oshimura M, Reeves RH
Dis Model Mech. 2023 Apr 1;16(4):dmm049712. doi: 10.1242/dmm.049712. Epub 2023 Apr 13. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
176937MRAP_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding MRAP and EmGFP-Bsd
176938IFNAR2_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding IFNAR2 and EmGFP-Bsd
176939IFNGR2_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding IFNGR2 and EmGFP-Bsd
176940TMEM50B_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding TMEM50B and EmGFP-Bsd
176941CRYZL1_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding CRYZL1 and EmGFP-Bsd
176942BACE2_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding BACE2 and EmGFP-Bsd
176943HMGN1_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding HMGN1 and EmGFP-Bsd
176944ABCG1_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding ABCG1 and EmGFP-Bsd
176945PDE9A_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding PDE9A and EmGFP-Bsd
176946NDUFV3_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding NDUFV3 and EmGFP-Bsd
176947HSF2BP_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding HSF2BP and EmGFP-Bsd
176948CFAP410_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding CFAP410 and EmGFP-Bsd
176949SUMO3_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding SUMO3 and EmGFP-Bsd
176950FAM207A_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding FAM207A and EmGFP-Bsd
176951SLC19A1_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding SLC19A1 and EmGFP-Bsd
176952S100B_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding S100B and EmGFP-Bsd
176953PRMT2_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding PRMT2 and EmGFP-Bsd
176954APP_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding APP and EmGFP-Bsd
176956RWDD2B_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding RWDD2B and EmGFP-Bsd
176957RRP1_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding RRP1 and EmGFP-Bsd
176958PCBP3_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding PCBP3 and EmGFP-Bsd
176960POFUT2_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding POFUT2 and EmGFP-Bsd
176961CBR3_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding CBR3 and EmGFP-Bsd
176963CLDN8_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding CLDN8 and EmGFP-Bsd
176964SOD1_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding SOD1 and EmGFP-Bsd
176966JAM2_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding JAM2 and EmGFP-Bsd
176968GLI1_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding GLI1 and EmGFP-Bsd
176969CHAF1B_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding CHAF1B and EmGFP-Bsd
176970GABPA_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding GABPA and EmGFP-Bsd
176972LRRC3_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding LRRC3 and EmGFP-Bsd
176973MIS18A_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding MIS18A and EmGFP-Bsd
176974RUNX1_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding RUNX1 and EmGFP-Bsd
176975MOSMO_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding MOSMO and EmGFP-Bsd
176976GNAS_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding GNAS and EmGFP-Bsd
176978Rcan1_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding Rcan1 and EmGFP-Bsd
176979DOP1B_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding DOP1B and EmGFP-Bsd
176980KCNE2_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding KCNE2 and EmGFP-Bsd
176981KCNJ15_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding KCNJ15 and EmGFP-Bsd
176982VPS26C_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding VPS26C and EmGFP-Bsd
176983ITGB2_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding ITGB2 and EmGFP-Bsd
176984WDR4_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding WDR4 and EmGFP-Bsd
176985GET1_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding GET1 and EmGFP-Bsd
176986CYYR1_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding CYYR1 and EmGFP-Bsd
176988DsRed2_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding DsRed2 and EmGFP-Bsd
176989TRAPPC10_pcDNA6.2/EmGFP-BsdMammalian expression vector encoding TRAPPC10 and EmGFP-Bsd
176991GNAS_pLENTI-CAG-IRES-GFPMammalian lentiviral expression vector encoding GNAS
176992GLI1_pLENTI-CAG-IRES-GFPMammalian lentiviral expression vector encoding GLI1
176993Sufu_pLENTI-CAG-IRES-GFPMammalian lentiviral expression vector encoding Sufu
176995HMGN1_pLENTI-CAG-IRES-GFPMammalian lentiviral expression vector encoding HMGN1
176996MIS18A_pLENTI-CAG-IRES-GFPMammalian lentiviral expression vector encoding MIS18A
176997JAM2_pLENTI-CAG-IRES-GFPMammalian lentiviral expression vector encoding JAM2
176998TRAPPC10_pLENTI-CAG-IRES-GFPMammalian lentiviral expression vector encoding TRAPPC10
176999GABPA_pLENTI-CAG-IRES-GFPMammalian lentiviral expression vector encoding GABPA
177000Rcan1_pLENTI-CAG-IRES-GFPMammalian lentiviral expression vector encoding Rcan1
177001RWDD2B_pLENTI-CAG-IRES-GFPMammalian lentiviral expression vector encoding RWDD2B
177004CRYZL1_pLENTI-CAG-IRES-GFPMammalian lentiviral expression vector encoding CRYZL1
177005ETS2_pLENTI-CAG-IRES-GFPMammalian lentiviral expression vector encoding ETS2
177006B3GALT5_pLENTI-CAG-IRES-GFPMammalian lentiviral expression vector encoding B3GALT5
177008CBR1_pLENTI-CAG-IRES-GFPMammalian lentiviral expression vector encoding CBR1
177009CHAF1B_pLENTI-CAG-IRES-GFPMammalian lentiviral expression vector encoding CHAF1B
177010DsRed2_pLENTI-CAG-IRES-GFPMammalian lentiviral expression vector encoding DsRed2

Antibodies from Article