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Paired CRISPR screens to map gene regulation in cis and trans

Xue X, Gajic ZZ, Caragine CM, Legut M, Walker C, Kim JYS, Wang X, Yan RE, Wessels H-H, Lu C, Bapodra N, Gürsoy G, Sanjana NE
bioRxiv 2024.11.27.625752 (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
217990pOT_7-lenti-EFS-SS1-BBz-2A-puroExpresses anti-Mesothelin CAR (with 4-1BB signaling domain) linked to puromycin resistance via P2A for lentiviral delivery.

Antibodies from Article