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Glutamine-rich regions of the disordered CREB transactivation domain mediate dynamic intra- and intermolecular interactions.

Martinez-Yamout MA, Nasir I, Shnitkind S, Ellis JP, Berlow RB, Kroon G, Deniz AA, Dyson HJ, Wright PE
Proc Natl Acad Sci U S A. 2023 Nov 21;120(47):e2313835120. doi: 10.1073/pnas.2313835120. Epub 2023 Nov 14. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
217978H6Gb1-CREB(1-100) bacterial expression of CREB1 domains
217980H6Gb1-CREB(160-280) bacterial expression of CREB1 domains
217981H6Gb1-CREB(1-280)bacterial expression of CREB1 domains
217982H6GB1-CREB(1-280) C90Abacterial expression of CREB1 domains
217983H6Gb1-CREB(1-280) C90A, T172Cbacterial expression of CREB1 domains
217984H6Gb1-CREB(85-160)bacterial expression of CREB1 domains
217985H6Gb1-CREB(1-280) A50C,C90Abacterial expression of CREB1 domains
220233H6Gb1-CREB(1-280) T160Cbacterial expression of CREB1 domains
220234H6Gb1-CREB(1-280) C90A, T172C, T259Cbacterial expression of CREB1 domains
220235H6Gb1-CREB(1-280) T2C, C90A, T198Cbacterial expression of CREB1 domains

Antibodies from Article