The USP46 complex deubiquitylates LRP6 to promote Wnt/beta-catenin signaling.
Ng VH, Spencer Z, Neitzel LR, Nayak A, Loberg MA, Shen C, Kassel SN, Kroh HK, An Z, Anthony CC, Bryant JM, Lawson A, Goldsmith L, Benchabane H, Hansen AG, Li J, D'Souza S, Lebensohn AM, Rohatgi R, Weiss WA, Weiss VL, Williams C, Hong CC, Robbins DJ, Ahmed Y, Lee E
Nat Commun. 2023 Oct 5;14(1):6173. doi: 10.1038/s41467-023-41836-z. PubMed Article
Ng VH, Spencer Z, Neitzel LR, Nayak A, Loberg MA, Shen C, Kassel SN, Kroh HK, An Z, Anthony CC, Bryant JM, Lawson A, Goldsmith L, Benchabane H, Hansen AG, Li J, D'Souza S, Lebensohn AM, Rohatgi R, Weiss WA, Weiss VL, Williams C, Hong CC, Robbins DJ, Ahmed Y, Lee E
Nat Commun. 2023 Oct 5;14(1):6173. doi: 10.1038/s41467-023-41836-z. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 217615 | Human USP46 | Mammalian expression of USP46 |
| 217618 | Human FLAG-WDR20 | Mammalian expression of FLAG tagged WDR20 |
| 217619 | Human FLAG-UAF1 S170Y | Mammalian expression of FLAG tagged mutant (UAF1 S170Y) UAF1 |