A fully human IgG1 antibody targeting connexin 32 extracellular domain blocks CMTX1 hemichannel dysfunction in an in vitro model.
Tettey-Matey A, Donati V, Cimmino C, Di Pietro C, Buratto D, Panarelli M, Reale A, Calistri A, Fornaini MV, Zhou R, Yang G, Zonta F, Marazziti D, Mammano F
Cell Commun Signal. 2024 Dec 5;22(1):589. doi: 10.1186/s12964-024-01969-0.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 216795 | pCW57-Cx32-IRES-GCaMP6s | Inducible bicistronic lentiviral plasmid for the simultaneous expression of Connexin 32 and cytosolic GCaMP6s |
| 216796 | pCW57-Cx32D178Y-IRES-GCaMP6s | Inducible bicistronic lentiviral plasmid for the simultaneous expression of the D178Y mutant form of Connexin 32 and cytosolic GCaMP6s |