ERK5 suppression overcomes FAK inhibitor resistance in mutant KRAS-driven non-small cell lung cancer.
Pozzato C, Outeiro-Pinho G, Galie M, Ramadori G, Konstantinidou G
EMBO Mol Med. 2024 Sep 13. doi: 10.1038/s44321-024-00138-7.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 216540 | pWZL-hygro-FAKWT | This retroviral plasmid expresses the human wild type PTK2 |
| 216541 | pWZL-hygro-FAKS732A | This retroviral plasmid expresses a mutated cDNA (dominant negative: S732A) of human PTK2 |
| 216542 | pWZL-hygro-FAKS910A | This retroviral plasmid expresses a mutated cDNA (dominant negative: S910A) of human PTK2 |
| 216543 | pWZL-hygro-FAKR177/178A | This retroviral plasmid expresses a mutated cDNA (dominant negative: R177/178A) of human PTK2 |
| 216544 | pWZL-hygro-FAKP712/713A | This retroviral plasmid expresses a mutated cDNA (dominant negative: P712/713A) of human PTK2 |
| 216545 | pWZL-hygro-FAKS722A | This retroviral plasmid expresses a mutated cDNA (dominant negative: S722A) of human PTK2 |
| 216546 | pWZL-hygro-FAKY861F | This retroviral plasmid expresses a mutated cDNA (dominant negative: Y861F) of human PTK2 |
| 216547 | pWZL-hygro-FAKY925F | This retroviral plasmid expresses a mutated cDNA (dominant negative: Y925F ) of human PTK2 |
| 216677 | pWZL-hygro-FAKY397F | This retroviral plasmid expresses a mutated cDNA (dominant negative: Y397F) of human PTK2 |
| 221642 | pWZL-hygro-FAKS732A/S910A | This retroviral plasmid expresses a double-mutated cDNA (dominant negative: S732A/S910A) of human PTK2 |