Cyclin E-induced replicative stress drives p53-dependent whole-genome duplication.
Zeng J, Hills SA, Ozono E, Diffley JFX
Cell. 2023 Feb 2;186(3):528-542.e14. doi: 10.1016/j.cell.2022.12.036. Epub 2023 Jan 20.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 216508 | pcDNA4/TO-cyclin E | Expresses cyclin E1 in human cells under a tetracycline/doxycycline-inducible promoter |
| 216509 | pcDNA4/TO-HRASG12V | Expresses HRAS with a G12V point mutation in human cells under a tetracycline/doxycycline-inducible promoter |
| 216510 | pcDNA4/TO-cMYC | Expresses MYC in human cells under a tetracycline/doxycycline-inducible promoter |
| 216511 | pcDNA4/TO-CDC25A | Expresses CDC25A in human cells under a tetracycline/doxycycline-inducible promoter |
| 217455 | PX459-TP53-exon4 | For TP53 knockout targeting exon 4 of TP53 |
| 217456 | PX459-TP53-exon5 | For TP53 knockout targeting exon 5 of TP53 |
| 217457 | PX459-CDKN1A | For CDKN1A (p21) knockout |