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Chemogenetic regulation of the TARP-lipid interaction mimics LTP and reversibly modifies behavior.

Park J, Berthoux C, Hoyos-Ramirez E, Shan L, Morimoto-Tomita M, Wang Y, Castillo PE, Tomita S
Cell Rep. 2023 Aug 29;42(8):112826. doi: 10.1016/j.celrep.2023.112826. Epub 2023 Jul 19. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
216257pGW1-ExSYTE-P2A-EGFPExSYTE (P2A) EGFP
216258pGW1-ExSYTE-P2A-EGFP-DTEExSYTE (P2A) EGFP with 3'UTR of Rat Arc DTE
216259pGW1-ExSYTE-EGFPExSYTE - EGFP fusion
216260pGW1-ExSYTE-EGFP-DTEExSYTE - EGFP fusion with 3'UTR of Rat Arc DTE
216262pAAV-Syn-ExSYTE.H64Ainactive ExSYTE.H64A (P2A) EGFP with 3'UTR of Rat Arc DTE under synapsin promoter
216263pAAV-Syn-FLEX-ExSYTECre-dependent expressoin of ExSYTE (P2A) EGFP with 3'UTR of Rat Arc DTE under synapsin promoter
216265pGEM-HE-ExSYTEExSYTE in oocyte vector
216266pEGFP-C2-DRDox-responsive module fused with EGFP
216269pEGFP-C2-KRf-TetRConstruct 2: Lipid binding domain KRφ - TetR
216270pEGFP-C2-TetR-KRf-TetRConstruct 3: TetR - Lipid binding domain KRφ - TetR

Antibodies from Article