Phage-assisted evolution of highly active cytosine base editors with enhanced selectivity and minimal sequence context preference.
Zhang E, Neugebauer ME, Krasnow NA, Liu DR
Nat Commun. 2024 Feb 24;15(1):1697. doi: 10.1038/s41467-024-45969-7.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 215819 | SpCas9-CBE6a | Express CBE6a (with SpCas9) in mammalian cells |
| 215820 | SpCas9-CBE6b | Express CBE6b (with SpCas9) in mammalian cells |
| 215821 | SpCas9-CBE6c | Express CBE6c (with SpCas9) in mammalian cells |
| 215822 | SpCas9-CBE6d | Express CBE6d (with SpCas9) in mammalian cells |
| 215824 | SpCas9-CBE6a-V106W | Express CBE6a-V106W (with SpCas9) in mammalian cells |
| 215825 | SpCas9-CBE6b-V106W | Express CBE6b V106W (with SpCas9) in mammalian cells |
| 215826 | SpCas9-CBE6c-V106W | Express CBE6c V106W (with SpCas9) in mammalian cells |
| 215827 | SpCas9-CBE6d-V106W | Express CBE6d V106W (with SpCas9) in mammalian cells |
| 215829 | eNme2C-CBE6a | Express CBE6a (with eNme2-C variant) in mammalian cells |
| 215830 | eNme2C-CBE6b | Express CBE6b (with eNme2-C variant) in mammalian cells |
| 215831 | eNme2C-CBE6c | Express CBE6c (with eNme2-C variant) in mammalian cells |
| 215832 | eNme2C-CBE6d | Express CBE6d (with eNme2-C variant) in mammalian cells |
| 215833 | SpCas9-CBE6a-IVT | Template for in vitro transcription of CBE6a (with SpCas9) |
| 215834 | SpCas9-CBE6b-IVT | Template for in vitro transcription of CBE6b (with SpCas9) |
| 215835 | SpCas9-CBE6c-IVT | Template for in vitro transcription of CBE6c (with SpCas9) |
| 215836 | SpCas9-CBE6d-IVT | Template for in vitro transcription of CBE6d (with SpCas9) |