Synthetic integrin antibodies discovered by yeast display reveal alphaV subunit pairing preferences with beta subunits.
Hao Y, Yan J, Fraser C, Jiang A, Anuganti M, Zhang R, Lloyd K, Jardine J, Coppola J, Meijers R, Li J, Springer TA
bioRxiv [Preprint]. 2024 Jan 27:2024.01.26.577394. doi: 10.1101/2024.01.26.577394.
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Plasmids from Article
No plasmids are currently publicly available from Addgene for this article.
Antibodies from Article
ID | Antibody | Purpose |
---|---|---|
213654 | Anti-Integrin alpha V beta 8 [IPI-ITGAV/ITGB8.8] | Anti-Integrin αVβ8 (Human) chimeric recombinant antibody with fused human variable and rabbit constant domains; binds the particular alpha/beta chain pair, does not block function. |
213655 | Anti-Integrin alpha V beta 6 [IPI-ITGAV/ITGB6.2] | Anti-Integrin αVβ6 (Human) chimeric recombinant antibody with fused human variable and rabbit constant domains; binds the particular alpha/beta chain pair, does not block function. |
213656 | Anti-Integrin alpha V beta 6 [IPI-ITGAV/ITGB6.3] | Anti-Integrin αVβ6 (Human) chimeric recombinant antibody with fused human variable and rabbit constant domains; binds the particular alpha/beta chain pair, blocks ligand binding/function (RGD-mimetic) |
213657 | Anti-Integrin alpha V beta 6 [IPI-ITGAV/ITGB6.4] | Anti-Integrin αVβ6 (Human) chimeric recombinant antibody with fused human variable and rabbit constant domains; binds the particular alpha/beta chain pair, blocks ligand binding/function (RGD-mimetic) |
213658 | Anti-Integrin alpha V beta 6 [IPI-ITGAV/ITGB6.12] | Anti-Integrin αVβ6 (Human) chimeric recombinant antibody with fused human variable and rabbit constant domains; binds the particular alpha/beta chain pair, blocks ligand binding/function (RGD-mimetic) |