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Chikungunya virus release is reduced by TIM-1 receptors through binding of envelope phosphatidylserine.

Reyes Ballista JM, Hoover AJ, Noble JT, Acciani MD, Miazgowicz KL, Harrison SA, Tabscott GAL, Duncan A, Barnes DN, Jimenez AR, Brindley MA
J Virol. 2024 Jul 15:e0077524. doi: 10.1128/jvi.00775-24. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
215694pcDNAintron-CHIKV-nsp1-c3xFLAGProduces the Chikungunya virus nonstructural protein 1 with a c-terminal 3xFLAG tag
215695pcDNAintron-CHIKV-nsp2-c3xFLAGProduces the Chikungunya virus nonstructural protein 2 with a c-terminal 3xFLAG tag
215696pcDNAintron-CHIKV-nsp3-c3xFLAGProduces the Chikungunya virus nonstructural protein 3 with a c-terminal 3xFLAG tag
215697pcDNAintron-CHIKV-nsp4-c3xFLAGProduces the Chikungunya virus nonstructural protein 4 with a c-terminal 3xFLAG tag
215698pcDNAintron-CHIKV-Structural polyproteinProduces the Chikungunya virus structural polyprotein Capsid-E3-E2-6K-E1
215699pcDNAintron-CHIKV-Structural polyprotein with Nluc tagged E2Produces the Chikungunya virus structural polyprotein Capsid-E3-NLucE2-6K-E1
215700pcDNAintron-CHIKV-Envelope proteinProduces the Chikungunya virus envelope protein E3-E2-6K-E1
215701pcDNAintron-CHIKV-capsid proteinProduces the Chikungunya virus capsid protein
215702pcDNAintron-CDC50A-c3xFLAGProduces human CDC50A-c3xFLAG, a chaperone to phosphatidylserine flippase complexes

Antibodies from Article