An RNA aptamer restores defective bone growth in FGFR3-related skeletal dysplasia in mice.
Kimura T, Bosakova M, Nonaka Y, Hruba E, Yasuda K, Futakawa S, Kubota T, Fafilek B, Gregor T, Abraham SP, Gomolkova R, Belaskova S, Pesl M, Csukasi F, Duran I, Fujiwara M, Kavkova M, Zikmund T, Kaiser J, Buchtova M, Krakow D, Nakamura Y, Ozono K, Krejci P
Sci Transl Med. 2021 May 5;13(592):eaba4226. doi: 10.1126/scitranslmed.aba4226.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 214908 | TR01F/hFGFR3-G380R-V5 | for PiggyBac mediated integration and stable expression of hFGFR3-G380R variant that is associated with Achondroplasia |