TEAD Inhibition Overcomes YAP1/TAZ-driven Primary and Acquired Resistance to KRASG12C Inhibitors.
Edwards AC, Stalnecker CA, Jean Morales A, Taylor KE, Klomp JE, Klomp JA, Waters AM, Sudhakar N, Hallin J, Tang TT, Olson P, Post L, Christensen JG, Cox AD, Der CJ
Cancer Res. 2023 Nov 7. doi: 10.1158/0008-5472.CAN-23-2994.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 213583 | pInducer-YAP1 | Doxycycline inducible expression of YAP1 wild type cDNA in mammalian cells |
| 213584 | pInducer-YAP1-S127A | Doxycycline inducible expression of YAP1-S127A cDNA in mammalian cells |
| 213585 | pInducer-YAP1-S127A/S397A | Doxycycline inducible expression of YAP1-S127A/S397A cDNA in mammalian cells |
| 213586 | pInducer-YAP1-S127A/S397A/S94A | Doxycycline inducible expression of YAP1-S127A/S397A/S94A cDNA in mammalian cells |
| 213587 | pInducer-TAZ | Doxycycline inducible expression of TAZ wild type cDNA in mammalian cells |
| 213588 | pInducer-TAZ-S89A | Doxycycline inducible expression of TAZ-S89A cDNA in mammalian cells |
| 213589 | pInducer-TAZ-S89A/S311A | Doxycycline inducible expression of TAZ-S89A/S311A cDNA in mammalian cells |
| 213590 | pInducer-TAZ-S89A/S311A/S51A | Doxycycline inducible expression of TAZ-S89A/S311A/S51A cDNA in mammalian cells |