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The I domain is a major recognition site on the leukocyte integrin Mac-1 (CD11b/CD18) for four distinct adhesion ligands.

Diamond MS, Garcia-Aguilar J, Bickford JK, Corbi AL, Springer TA
J Cell Biol. 1993 Feb . 120(4):1031-43. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

No plasmids are currently publicly available from Addgene for this article.

Antibodies from Article

ID Antibody Purpose
213667 Anti-Integrin alpha M [IPI-CBRM1/29] Anti-Integrin αM (Human) chimeric recombinant antibody with fused mouse variable and rabbit constant domains; binds αM subunit; blocks ligand binding/function.
213677 Anti-Integrin alpha M [IPI-CBRM1/29] Anti-Integrin αM (Human) recombinant mouse monoclonal antibody; binds αM subunit; blocks ligand binding/function. For more data, see Antibody 213667.