Joint genotypic and phenotypic outcome modeling improves base editing variant effect quantification.
Ryu J, Barkal S, Yu T, Jankowiak M, Zhou Y, Francoeur M, Phan QV, Li Z, Tognon M, Brown L, Love MI, Bhat V, Lettre G, Ascher DB, Cassa CA, Sherwood RI, Pinello L
Nat Genet. 2024 Apr 24. doi: 10.1038/s41588-024-01726-6.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 213008 | lentiCRISPRv2FE-ABE8e-SpRY | A lentiviral vector expressing the ABE8e-SpRY base editor and an sgRNA cloning site |
| 213009 | pLenti_ABE8e-SpRY-P2A-BFP_HygroR | A lentiviral vector used to create stable cell lines expressing the ABE8e-SpRY base editor and BFP |