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SARS-CoV-2 Omicron XBB lineage spike structures, conformations, antigenicity, and receptor recognition.

Zhang QE, Lindenberger J, Parsons R, Thakur B, Parks R, Park CS, Huang X, Sammour S, Janowska K, Spence TN, Edwards RJ, Martin M, Williams WB, Gobeil S, Montefiori DC, Korber B, Saunders KO, Haynes BF, Haynes BF, Henderson R, Acharya P
bioRxiv [Preprint]. 2024 Mar 12:2024.02.12.580004. doi: 10.1101/2024.02.12.580004. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
212990pαH-S-GSAS/EG.5Mammalian cell expression of SARS-CoV-2 Spike protein of OMICRON.EG5 variant
212991pαH-S-GSAS/XBB.1.5"Mammalian cell expression of SARS-CoV-2 Spike protein of Omicron.XBB.1.5 variant
212992pαH-S-GSAS/XBB.1.16Mammalian cell expression of SARS-CoV-2 Spike protein of Omicron.XBB.1.16
212993pαH-S-RRAR/XBB.1.5Mammalian cell expression of SARS-CoV-2 Spike protein of Omicron.XBB.1.5 with with furin side intact
213037pαH-S-RRAR/XBB.1.16Mammalian cell expression of SARS-CoV-2 Spike protein of Omicron.XBB.1.16 with with furin side intact
213038pCAGGS/XBB.1.5-RBDMammalian cell expression of SARS-CoV-2 Spike RBD protein of OMICRON.XBB.1.5 variant
213069pαH-S-GSAS-OMICRON.BA.5Mammalian cell expression of SARS-CoV-2 Spike protein of Omicron.5 variant
213070pCAGGS/XBB.1.16-RBDMammalian cell expression of SARS-CoV-2 Spike RBD protein of OMICRON.XBB.1.16 variant
213071pαH-S-RRAR-OMICRON.BA.5Mammalian cell expression of SARS-CoV-2 Spike protein of Omicron.5 with with furin side intact
213410pCAGGS/EG5-RBDMammalian cell expression of SARS-CoV-2 Spike RBD protein of OMICRON.EG5 variant
213478pCAGGS-Omicron.BA.5-RBDMammalian cell expression of SARS-CoV-2 Spike RBD protein of OMICRON.BA.5 variant
213828pαH-S-GSAS-2P-Omicron-BA.5Mammalian cell expression of SARS-CoV-2 Spike protein of OMICRON.2P.BA5 variant
218668pαH-S-GSAS/EG.5.1Mammalian cell expression of SARS-CoV-2 Spike protein of OMICRON.EG.5.1 variant

Antibodies from Article