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Engineering TALE-linked deaminases to facilitate precision adenine base editing in mitochondrial DNA.

Cho SI, Lim K, Hong S, Lee J, Kim A, Lim CJ, Ryou S, Lee JM, Mok YG, Chung E, Kim S, Han S, Cho SM, Kim J, Kim EK, Nam KH, Oh Y, Choi M, An TH, Oh KJ, Lee S, Lee H, Kim JS
Cell. 2024 Jan 4;187(1):95-109.e26. doi: 10.1016/j.cell.2023.11.035. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
212949TALED_ Left-mouse-mtRnr1_A1555G-8e-E1347AExpresses TALED_ Left-mouse-mtRnr1_A1555G-8e-E1347A in mammalian cells
212950TALED_Left-Cox3.1-1397N.Expresses TALED_Left-Cox3.1-1397N. in mammalian cells
212951TALED_Left-mouse-ATP6-1397N.Expresses TALED_Left-mouse-ATP6-1397N in mammalian cells
212952TALED_Left-ND6-1397NExpresses TALED_Left-ND6-1397N in mammalian cells
212953TALED_Right-Cox3.1-1397C-AD.ExpressesTALED_Right-Cox3.1-1397C-AD in mammalian cells
212954TALED_Right-mouse-ATP6-1397C-ADExpresses TALED_Right-mouse-ATP6-1397C-AD in mammalian cells
212955TALED_Right-mouse-ATP6-1397C-AD(V28R)Expresses TALED_Right-mouse-ATP6-1397C-AD(V28R) in mammalian cells
212956TALED_Right-ND6-1397C-ADExpresses TALED_Right-ND6-1397C-AD in mammalian cells

Antibodies from Article