An intermediate Rb-E2F activity state safeguards proliferation commitment.
Konagaya Y, Rosenthal D, Ratnayeke N, Fan Y, Meyer T
Nature. 2024 Jul;631(8020):424-431. doi: 10.1038/s41586-024-07554-2. Epub 2024 Jun 26.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 212665 | pLV-hCDC6p-Venus | Express Venus under CDC6 promoter |
| 212666 | pLV-hCDC6p-Venus-puro | Express Venus under CDC6 promoter |
| 212667 | pLV-EF1a-DHB-mTurq2 | Express tagged DHB |
| 212668 | pLV-EF1a-H2B-miRFP670 | Express tagged H2B |
| 212669 | pCW-CCNE1-HA-puro | Express tagged cyclin E1 |
| 212670 | pCW-CCND1-HA-puro | Express tagged cyclin D1 |
| 212671 | pCW-12S-E1A-HA-puro | Express adenovirus E1A |
| 212672 | pCW-HA-hRb-WT-puro | Express tagged hRb |
| 212673 | pCW-HA-hRb-delta-CDK-puro | Express tagged hRb delta-CDK phosphosite mutant |
| 212674 | pCW-HA-hRb-WT-T373A-S608A-S612A-puro | Express tagged hRb mutant |
| 212675 | pCW-HA-hRb-delta-CDK-T373D-S608D-S612D-puro | Express tagged hRb phosphosite mutant |