CRISPR-Cas13d screens identify KILR, a breast cancer risk-associated lncRNA that regulates DNA replication and repair.
Wang L, Bitar M, Lu X, Jacquelin S, Nair S, Sivakumaran H, Hillman KM, Kaufmann S, Ziegman R, Casciello F, Gowda H, Rosenbluh J, Edwards SL, French JD
Mol Cancer. 2024 May 15;23(1):101. doi: 10.1186/s12943-024-02021-y.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 212196 | pLX_TRC311/NLS-Cas13d-P2A-Blast | CasRx (NLS-RfxCas13d-NLS) with 2A-Blasticidin for RNA targeting. CasRx-2A-Blasticidin is driven by EF1a promoter. EGFP is driven by SV40 |