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Engineered virus-like particles for transient delivery of prime editor ribonucleoprotein complexes in vivo.

An M, Raguram A, Du SW, Banskota S, Davis JR, Newby GA, Chen PZ, Palczewski K, Liu DR
Nat Biotechnol. 2024 Jan 8. doi: 10.1038/s41587-023-02078-y. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
211370gag-MCP-polPackaging plasmid for v3 PE-eVLP production
211371gag-PEPackaging plasmid for v3 PE-eVLP production
211372MS2-epegRNA-Dnmt1Dnmt1 targeting epegRNA with MS2 insertion in gRNA scaffold for v3 PE-eVLP production
211373gag-COM-polPackaging plasmid for v3b PE-eVLP production
211374gag-P3-polPackaging plasmid for v3b PE-eVLP production
211375P4-PEPackaging plasmid for v3b PE-eVLP production
211376COM-epegRNA-Dnmt1Dnmt1 targeting epegRNA with COM insertion in gRNA scaffold for v3b PE-eVLP production
225143P4-TadCBEdPackaging plasmid for TadCBEd in v3b PE-eVLP architecture
225144gag-TadCBEdPackaging plasmid for TadCBEd in v3 PE-eVLP architecture

Antibodies from Article