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Mitotic chromosomes are self-entangled and disentangle through a topoisomerase-II-dependent two-stage exit from mitosis.

Hildebrand EM, Polovnikov K, Dekker B, Liu Y, Lafontaine DL, Fox AN, Li Y, Venev SV, Mirny LA, Dekker J
Mol Cell. 2024 Mar 13:S1097-2765(24)00144-8. doi: 10.1016/j.molcel.2024.02.025. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
211115pUC19-Top2A-5X Gly-Venus-T2A-HygroFor tagging the C-term of Top2A with Venus

Antibodies from Article