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A noncanonical function of SKP1 regulates the switch between autophagy and unconventional secretion.

Li J, Krause GJ, Gui Q, Kaushik S, Rona G, Zhang Q, Liang FX, Dhabaria A, Anerillas C, Martindale JL, Vasilyev N, Askenazi M, Ueberheide B, Nudler E, Gorospe M, Cuervo AM, Pagano M
Sci Adv. 2023 Oct 13;9(41):eadh1134. doi: 10.1126/sciadv.adh1134. Epub 2023 Oct 13. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
213423Flag-SKP1-K142RExpresses human SKP1 K142R mutant in mammalian cells
213424Flag-SKP1-K163RExpresses human SKP1 K163R mutant in mammalian cells
213425Flag-SKP1-RR (K142R/K163R)Expresses human SKP1 K142R/K163R mutant in mammalian cells
213482Flag-SKP1-T131AExpresses human SKP1 T131A mutant in mammalian cells
213600Flag-SKP1-T131DExpresses human SKP1 T131D mutant in mammalian cells
213601Flag-SKP1-T131EExpresses human SKP1 T131E mutant in mammalian cells
213642Flag-SKP1-97-101-5AExpresses human SKP1-97-101-5A mutant in mammalian cells
213643Flag-SKP1-113-117-5AExpresses human SKP1-113-117-5A mutant in mammalian cells
213644Flag-SKP1-120-124-5AExpresses human SKP1-120-124-5A mutant in mammalian cells
213645Flag-SKP1-138-142-5AExpresses human SKP1-138-142-5A mutant in mammalian cells
213687Flag-SKP1-F139A/I141AExpresses human SKP1-F139A/I141A mutant in mammalian cells
213690pET-24d-Flag-SKP1Expresses human SKP1 in bacteria cells
213734pBabe-Flag-SKP1-T131AExpresses human SKP1 T131A mutant in mammalian cells

Antibodies from Article