Correction of a homoplasmic mitochondrial tRNA mutation in patient-derived iPSCs via a mitochondrial base editor.
Chen X, Chen M, Zhu Y, Sun H, Wang Y, Xie Y, Ji L, Wang C, Hu Z, Guo X, Xu Z, Zhang J, Yang S, Liang D, Shen B
Commun Biol. 2023 Nov 3;6(1):1116. doi: 10.1038/s42003-023-05500-y.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 210395 | PB-CAG-4300-H2-G1397C | To correct m.A4300G mutation on mtDNA |
| 210396 | PB-CAG-4300-L1-G1397N | To correct m.A4300G mutation on mtDNA |