Exploring the "misfolding problem" by systematic discovery and analysis of functional-but-degraded proteins.
Flagg MP, Lam B, Lam DK, Le TM, Kao A, Slaiwa YI, Hampton RY
Mol Biol Cell. 2023 Dec 1;34(13):ar125. doi: 10.1091/mbc.E23-06-0248. Epub 2023 Sep 20.
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Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 210143 | pRH2941 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::ARO7-GFP::tADH1 |
| 210144 | pRH2961 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::LYS1-GFP::tADH1 |
| 210145 | pRH3002 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::lys1-W353R-GFP::tADH1 |
| 210146 | pRH3015 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::lys1-L29P-GFP::tADH1 |
| 210147 | pRH3016 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::lys1-V26D-GFP::tADH1 |
| 210148 | pRH3038 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::lys1-L146P-GFP::tADH1 |
| 210149 | pRH3039 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::lys1-W151G-GFP::tADH1 |
| 210150 | pRH3040 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::lys1-W151R-GFP::tADH1 |
| 210151 | pRH3041 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::lys1-W151P-GFP::tADH1 |
| 210152 | pRH3042 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::lys1-W151E-GFP::tADH1 |
| 210153 | pRH3043 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::lys1-W151S-GFP::tADH1 |
| 210154 | pRH3044 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::lys1-W151T-GFP::tADH1 |
| 210155 | pRH3045 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::lys1-W151C-GFP::tADH1 |
| 210156 | pRH3046 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::lys1-W151L-GFP::tADH1 |
| 210157 | pRH3047 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::lys1-W151H-GFP::tADH1 |
| 210158 | pRH3048 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::lys1-W151Y-GFP::tADH1 |
| 210159 | pRH3053 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::lys1-W151A-GFP::tADH1 |
| 210160 | pRH3054 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::lys1-W151F-GFP::tADH1 |
| 210161 | pRH3055 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::lys1-W151Q-GFP::tADH1 |
| 210162 | pRH3057 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::lys1-I36D-GFP::tADH1 |
| 210163 | pRH3069 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::lys1-W151V-GFP::tADH1 |
| 210164 | pRH3105 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::lys1-P194Q-GFP::tADH1 |
| 210165 | pRH3128 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::ADE1-GFP::tADH1 |
| 210166 | pRH3135 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::lys1-I245N-GFP::tADH1 |
| 210167 | pRH3139 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::aro7-R33G-GFP::tADH1 |
| 210168 | pRH3142 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::aro7-D147G-GFP::tADH1 |
| 210169 | pRH3145 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::aro7-D147V-GFP::tADH1 |
| 210170 | pRH3148 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::ade1-D37V-GFP::tADH1 |
| 210171 | pRH3150 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::ade1-W64R-GFP::tADH1 |
| 210172 | pRH3152 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::ade1-G54E-GFP::tADH1 |
| 210173 | pRH3153 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::ade1-L102P-GFP::tADH1 |
| 210174 | pRH3154 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::ade1-L32P-GFP::tADH1 |
| 210175 | pRH3155 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::ade1-L32R-GFP::tADH1 |
| 210176 | pRH3168 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::ade1-A195D-GFP::tADH1 |
| 210177 | pRH3175 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::aro7-R33G,G141S-GFP::tADH1 |
| 210178 | pRH3176 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::aro7-G141S-GFP::tADH1 |
| 210179 | pRH3178 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::ade1-G54V-GFP::tADH1 |
| 210180 | pRH3180 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::ade1-G54R-GFP::tADH1 |
| 210181 | pRH3186 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::lys1-W353G-GFP::tADH1 |
| 210182 | pRH3214 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::lys1-W151D-GFP::tADH1 |
| 210183 | pRH3215 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::lys1-W151I-GFP::tADH1 |
| 210184 | pRH3216 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::lys1-W151K-GFP::tADH1 |
| 210185 | pRH3217 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::lys1-W151M-GFP::tADH1 |
| 210186 | pRH3218 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::lys1-W151N-GFP::tADH1 |
| 210187 | pRH3243 | Protein quality control substrate and associated control YIp ADE2-LEU2 pTDH3::aro7-R33P-GFP::tADH1 |