Single-molecule characterization of subtype-specific beta1 integrin mechanics.

Jo MH, Li J, Jaumouille V, Hao Y, Coppola J, Yan J, Waterman CM, Springer TA, Ha T
Nat Commun. 2022 Dec 3;13(1):7471. doi: 10.1038/s41467-022-35173-w. PubMed Article

Plasmids from Article

No plasmids are currently publicly available from Addgene for this article.

Antibodies from Article

ID	Antibody	Purpose
209611	Anti-Integrin alpha 5 beta 1 [IPI-ITGA5/ITGB1.2]	Anti-Integrin α5β1 (Human) chimeric recombinant antibody with fused human variable and rabbit constant domains; binds the particular alpha/beta chain pair, does not block function
213652	Anti-Integrin alpha 5 beta 1 [IPI-ITGA5/ITGB1.4]	Anti-Integrin α5β1 (Human) chimeric recombinant antibody with fused human variable and rabbit constant domains; binds the particular alpha/beta chain pair, does not block function
213653	Anti-Integrin alpha V beta 8 [IPI-ITGAV/ITGB8.1]	Anti-Integrin αVβ8 (Human) chimeric recombinant antibody with fused human variable and rabbit constant domains; binds the particular alpha/beta chain pair, does not block function
213659	Anti-Integrin alpha V beta 5 [IPI-ITGAV/ITGB5.9]	Anti-Integrin αVβ5 (Human) chimeric recombinant antibody with fused human variable and rabbit constant domains; binds the particular alpha/beta chain pair, blocks ligand binding/function (RGD-mimetic)
213660	Anti-Integrin alpha V beta 3 [IPI-ITGAV/ITGB3.7]	Anti-Integrin αVβ3 (Human) chimeric recombinant antibody with fused human variable and rabbit constant domains; binds the particular alpha/beta chain pair, blocks ligand binding/function (RGD-mimetic)
213661	Anti-Integrin alpha V beta 3 [IPI-ITGAV/ITGB3.13]	Anti-Integrin αVβ3 (Human) chimeric recombinant antibody with fused human variable and rabbit constant domains; binds the particular alpha/beta chain pair, blocks ligand binding/function (RGD-mimetic)