A split and inducible adenine base editor for precise in vivo base editing.
Zeng H, Yuan Q, Peng F, Ma D, Lingineni A, Chee K, Gilberd P, Osikpa EC, Sun Z, Gao X
Nat Commun. 2023 Sep 11;14(1):5573. doi: 10.1038/s41467-023-41331-5.
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Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 209553 | sABE v3.22_N | pCMV-bpSV40 NLS-TadA8e(2-76)-2xFRB-BGHpA |
| 209554 | sABE v3.22_C | pCMV-SV40_NLS-2xFKBP3-TadA-8e(77-167)-SpCas9(D10A)-SV40_NLS-BGHpA |
| 209555 | sABE v3.22 Lenti_1 | pCMV-SV40NLS-2xFKBP3-TadA-8e(77-167)-SpCas9(D10A, 2-468)-gp41-1_IntN |
| 209556 | sABE v3.22 Lenti_2 | pU6-SpCas9_sgRNA-pCMV-bpSV40_NLS-TadA-8e (2-76)-2xFRB |