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Nature-inspired dimerization as a strategy to modulate neuropeptide pharmacology exemplified with vasopressin and oxytocin.

Dekan Z, Kremsmayr T, Keov P, Godin M, Teakle N, Durrauer L, Xiang H, Gharib D, Bergmayr C, Hellinger R, Gay M, Vilaseca M, Kurzbach D, Albericio F, Alewood PF, Gruber CW, Muttenthaler M
Chem Sci. 2021 Feb 4;12(11):4057-4062. doi: 10.1039/d0sc05501h. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
208913OTR untaggedencodes the human oxytocin receptor, without any tags

Antibodies from Article