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Optogenetic clustering and membrane translocation of the BcLOV4 photoreceptor.

Pal AA, Benman W, Mumford TR, Huang Z, Chow BY, Bugaj LJ
Proc Natl Acad Sci U S A. 2023 Aug 8;120(32):e2221615120. doi: 10.1073/pnas.2221615120. Epub 2023 Aug 1. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
208274BcLOV-mCh-EGFRExpresses BcLOV-EGFR for optogenetic activation of EGFR signaling. Includes an mCherry tag.
208275Fus-BcLOV-mCh-SOSExpresses Fus-BcLOV-SOS for optogenetic activation of Ras/Erk signaling. Includes an mCherry tag.
208276RGG-BcLOV-mChExpresses RGG-BcLOV fusion for optogenetic membrane recruitment. Includes an mCherry tag.
208277Fus-BcLOV-mChExpresses Fus-BcLOV fusion for optogenetic membrane recruitment. Includes an mCherry tag.
208278RGG-BcLOV-mCh-SOSExpresses RGG-BcLOV-SOS for optogenetic activation of Ras/Erk signaling. Includes an mCherry tag.
208279BcLOV-mCh-SOSExpresses BcLOV-SOS for optogenetic activation of Ras/Erk signaling. Includes an mCherry tag.
208280RGG-BcLOV-mCh-EGFRExpresses RGG-BcLOV-EGFR for optogenetic activation of EGFR signaling. Includes an mCherry tag.
208281Fus-BcLOV-mCh-EGFRExpresses Fus-BcLOV-EGFR for optogenetic activation of EGFR signaling. Includes an mCherry tag.

Antibodies from Article