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Folate depletion induces erythroid differentiation through perturbation of de novo purine synthesis.

Maynard AG, Pohl NK, Mueller AP, Petrova B, Wong AYL, Wang P, Culhane AJ, Brook JR, Hirsch LM, Hoang N, Kirkland O, Braun T, Ducamp S, Fleming MD, Li H, Kanarek N
Sci Adv. 2024 Feb 2;10(5):eadj9479. doi: 10.1126/sciadv.adj9479. Epub 2024 Jan 31. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
208049pLenti-sgAMPKa1-Cas9-GFPLentiviral vector expressing Cas9 and an sgRNA targeting AMPKa1

Antibodies from Article