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All-optical closed-loop voltage clamp for precise control of muscles and neurons in live animals.

Bergs ACF, Liewald JF, Rodriguez-Rozada S, Liu Q, Wirt C, Bessel A, Zeitzschel N, Durmaz H, Nozownik A, Dill H, Jospin M, Vierock J, Bargmann CI, Hegemann P, Wiegert JS, Gottschalk A
Nat Commun. 2023 Apr 6;14(1):1939. doi: 10.1038/s41467-023-37622-6. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
214888pAB17 (punc-17::QuasAr)Expresses the voltage sensor QuasAr2 in cholinergic neurons of C. elegans.
214889pAB26 (punc-17::GtACR2::mCerulean::βHK::Chrimson)Expresses the optogenetic tool BiPOLES in cholinergic neurons of C. elegans.
214890pAB27 (pmyo-3::GtACR2::mCerulean::βHK::Chrimson)Expresses the optogenetic tool BiPOLES in BWMs of C. elegans.
214891pAB31 (punc-47::GtACR2::mCerulean::bHK::Chrimson)Expresses the optogenetic tool BiPOLES in GABAergic neurons of C. elegans.

Antibodies from Article