The SUMO-NIP45 pathway processes toxic DNA catenanes to prevent mitotic failure.
Hertz EPT, Vega IA, Kruse T, Wang Y, Hendriks IA, Bizard AH, Eugui-Anta A, Hay RT, Nielsen ML, Nilsson J, Hickson ID, Mailand N
Nat Struct Mol Biol. 2023 Jul 20. doi: 10.1038/s41594-023-01045-0. PubMed Article
Hertz EPT, Vega IA, Kruse T, Wang Y, Hendriks IA, Bizard AH, Eugui-Anta A, Hay RT, Nielsen ML, Nilsson J, Hickson ID, Mailand N
Nat Struct Mol Biol. 2023 Jul 20. doi: 10.1038/s41594-023-01045-0. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 210262 | EGFP-NIP45 wt | Inducible expression of N-terminally EGFP-tagged NIP45 wt resistant to siRNA. Use with Flp-In T-Rex system. |
| 210263 | EGFP-NIP45 delta-SLD2 | Inducible expression of N-terminally EGFP-tagged NIP45 delta-SLD2. Use with Flp-In T-Rex system. |
| 210264 | EGFP-NIP45 delta-SLD1 | Inducible expression of N-terminally EGFP-tagged NIP45 delta-SLD1. Use with Flp-In T-Rex system. |
| 210265 | EGFP-NIP45 D394R | Inducible expression of N-terminally EGFP-tagged NIP45 D394R resistant to siRNA. Use with Flp-In T-Rex system. |
| 210266 | mCherry-NIP45 wt | Inducible expression of N-terminally mCherry-tagged NIP45 wt resistant to siRNA. Use with Flp-In T-Rex system. |
| 210267 | mCherry-NIP45 D394R | Inducible expression of N-terminally mCherry-tagged NIP45 D394R resistant to siRNA. Use with Flp-In T-Rex system. |
| 210268 | EGFP-NIP45 delta-N1 | Inducible expression of N-terminally EGFP-tagged NIP45 delta-N1 resistant to siRNA. Use with Flp-In T-Rex system. |
| 210269 | EGFP-NIP45 delta-N2 | Inducible expression of N-terminally EGFP-tagged NIP45 delta-N2 resistant to siRNA. Use with Flp-In T-Rex system. |
| 210270 | pcDNA5-FRT-TO-EGFP-N | N-terminal EGFP-tagging of inserts for inducible expression. Use with Flp-In T-Rex system. |
| 210271 | pcDNA5-FRT-TO-mCherry-N | N-terminal mCherry-tagging of inserts for inducible expression. Use with Flp-In T-Rex system. |