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The pioneer factor SOX9 competes for epigenetic factors to switch stem cell fates.

Yang Y, Gomez N, Infarinato N, Adam RC, Sribour M, Baek I, Laurin M, Fuchs E
Nat Cell Biol. 2023 Jul 24. doi: 10.1038/s41556-023-01184-y. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
203962plko_TRE3G_Myc-Sox9WT_PGKpuroRDox inducible WT SOX9 with myc tag
203963plko_TRE3G_Myc-Sox9HMGonlySTOP_PGKpuroRDox inducible myc tag truncated SOX9 without trans-activating domain (noTA)
203964plko_TRE3G_nlsMyc-Sox9HMGtruncation_PGKpuroRDox inducible myc tag truncated SOX9 without DNA-binding domain (noHMG)
203965pT5_TRE-ARID1A-FLAG_PGK-H2B-RFPDox inducible FLAG tag ARID1a in a sleeping beauty transposon construct

Antibodies from Article