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Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications.
Hu C, Myers MT, Zhou X, Hou Z, Lozen ML, Nam KH, Zhang Y, Ke A
Mol Cell. 2024 Feb 1;84(3):463-475.e5. doi: 10.1016/j.molcel.2023.12.034. Epub 2024 Jan 18. PubMed Article

Plasmids from Article

ID Plasmid Purpose
207394pSmart-EF1alpha-NlaCas7-p65Expresses NlaCas7-p65 activator fusion in mammalian cells
207395pSmart-EF1alpha-AcrIC8-NLSExpresses AcrIC8 with NLS in mammalian cells
207396pSmart-EF1alpha-AcrIE2-NLSExpresses AcrIE2 with NLS in mammalian cells
207397pSmart-EF1alpha-AcrIC9-NLSExpresses AcrIC9 with NLS in mammalian cells
207409pET28b-TEV-AcrIC9Protein purification vector to produce AcrIC9 in E. coli
207410pRSFDuet-3C-AcrIC8Protein purification vector to produce AcrIC8 in E. coli

Antibodies from Article