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Kinetic Characterization and Inhibition of Trypanosoma cruzi Hypoxanthine-Guanine Phosphoribosyltransferases.

Glockzin K, Kostomiris D, Minnow YVT, Suthagar K, Clinch K, Gai S, Buckler JN, Schramm VL, Tyler PC, Meek TD, Katzfuss A
Biochemistry. 2022 Oct 4;61(19):2088-2105. doi: 10.1021/acs.biochem.2c00312. Epub 2022 Sep 15. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
206980SpIMPDHStreptococcus pyogenes Inosine 5′-Monophosphate Dehydrogenase (SpIMPDH, EC. 1.1.1.205). Contains His6 tag with TEV protease cleavage site in pET-28b(+) plasmid for protein expression.

Antibodies from Article