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Fluorogenic reporter enables identification of compounds that inhibit SARS-CoV-2.

Yang J, Xiao Y, Lidsky PV, Wu CT, Bonser LR, Peng S, Garcia-Knight MA, Tassetto M, Chung CI, Li X, Nakayama T, Lee IT, Nayak JV, Ghias K, Hargett KL, Shoichet BK, Erle DJ, Jackson PK, Andino R, Shu X
Nat Microbiol. 2023 Jan;8(1):121-134. doi: 10.1038/s41564-022-01288-5. Epub 2023 Jan 5. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
206957pCDNA3.1-spikeRBD::∆ACE2 SURFFluorescent reporter of the interaction between SARS-CoV-2 spike and human ACE2

Antibodies from Article