An engineered Sox17 induces somatic to neural stem cell fate transitions independently from pluripotency reprogramming.
Weng M, Hu H, Graus MS, Tan DS, Gao Y, Ren S, Ho DHH, Langer J, Holzner M, Huang Y, Ling GS, Lai CSW, Francois M, Jauch R
Sci Adv. 2023 Aug 25;9(34):eadh2501. doi: 10.1126/sciadv.adh2501. Epub 2023 Aug 23.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 206384 | pHAGE2-TetO-hSOX17FNV | Expresses human SOX17FNV in mammalian cells, for lentivirus generation. |
| 206385 | pHAGE2-TetO-hSOX2-C17 | Expresses human SOX2-C17 in mammalian cells, for lentivirus generation. |
| 206386 | pHAGE2-TetO-hKLF4 | Expresses human KLF4 in mammalian cells, for lentivirus generation. |
| 206387 | pHAGE2-TetO-hcMYC | Expresses human c-MYC in mammalian cells, for lentivirus generation. |
| 206388 | pHAGE2-TetO-hSOX2 | Expresses human SOX2 in mammalian cells, for lentivirus generation. |
| 206389 | pHAGE2-TetO-hSOX17 | Expresses human SOX17 in mammalian cells, for lentivirus generation. |
| 206390 | pLVTHM-mBrn2-3xflag | Expresses 3xflag fused mouse BRN2 in mammalian cells, for lentivirus generation. |
| 206391 | Halo-tagged Sox17FNV | Expresses Halo-tagged mouse SOX17FNV in mammalian cells, for single-molecule tracking. |