Txnip deletions and missense alleles prolong the survival of cones in a retinitis pigmentosa mouse model.
Xue Y, Zhou Y, Cepko CL
Elife. 2024 May 10;12:RP90749. doi: 10.7554/eLife.90749.
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PubMed
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Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 206348 | AAV-Best1-N.Txnip | AAV plasmid expressing deltion TXNIP in retinal pigment epithelium |
| 206349 | AAV-Best1-C.Txnip(C247S) | AAV plasmid expressing deltion and mutant TXNIP in retinal pigment epithelium |
| 206350 | AAV-Best1-C.Txnip(C247S_LL351-352AA) | AAV plasmid expressing deltion and mutant TXNIP in retinal pigment epithelium |
| 206351 | AAV-Best1-sC.Txnip | AAV plasmid expressing deltion TXNIP in retinal pigment epithelium |
| 206352 | AAV-Best1-nt.Txnip(C247S)(1-320aa) | AAV plasmid expressing deltion and mutant TXNIP in retinal pigment epithelium |
| 206353 | AAV-CMV-Txnip(C247S) | AAV plasmid expressing mutant TXNIP |
| 206354 | AAV-RedO-nt.Txnip(C247S)(1-301aa) | AAV plasmid expressing deltion and mutant TXNIP in photoreceptors |
| 206355 | AAV-RO1.7-Hsp90ab1-FLAG | AAV plasmid expressing FLAG-tagged HSP90AB1 in photoreceptors |
| 206356 | AAV-RedO-shNC | AAV plasmid expressing non-targeting control shRNA in photoreceptors |
| 206357 | AAV-RedO-shHsp90ab1 (#a) | AAV plasmid expressing HSP90AB1 shRNA in photoreceptors |
| 206359 | AAV-RedO-shHsp90ab1(#c) | AAV plasmid expressing HSP90AB1 shRNA in photoreceptors |