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In vitro and in vivo modelling of mutant JAK3/STAT5 signaling in leukemia.

Omari SA, Kosasih HJ, Chung T, de Bock CE
Heliyon. 2023 Nov 8;9(11):e22085. doi: 10.1016/j.heliyon.2023.e22085. eCollection 2023 Nov. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
206290MSCV-JAK3(M511)_IRES_GFPExpression of mutant JAK3 (M511I) that is able to drive constitutive activation of the JAK/STAT pathway
206291MSCV_JAK3_IRES_BFPExpresses the wild type form of human JAK3.

Antibodies from Article