Glycosphingolipid synthesis mediates immune evasion in KRAS-driven cancer.
Soula M, Unlu G, Welch R, Chudnovskiy A, Uygur B, Shah V, Alwaseem H, Bunk P, Subramanyam V, Yeh HW, Khan A, Heissel S, Goodarzi H, Victora GD, Beyaz S, Birsoy K
Nature. 2024 Aug 7. doi: 10.1038/s41586-024-07787-1.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 206248 | Mouse lipid metabolism knockout library | The lipid metabolism library contains guide RNAs against 295 genes targeting mouse genes encoding enzymes that directly impact lipid metabolism. |
| 206249 | Mouse sphingolipid metabolism knockout library | The sphingolipid metabolism library targets 82 mouse genes in the de novo ceramide and downstream sphingolipid metabolism pathways. |