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RAB3 phosphorylation by pathogenic LRRK2 impairs trafficking of synaptic vesicle precursors.

Dou D, Aiken J, Holzbaur ELF
J Cell Biol. 2024 Jun 3;223(6):e202307092. doi: 10.1083/jcb.202307092. Epub 2024 Mar 21. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
206145PGK mScarlet-SynaptophysinPGK mScarlet-Synaptophysin
206146PGK EGFP-RAB3A-WTPGK EGFP-RAB3A-WT
206148PGK EGFP-RAB3A-T86EPGK EGFP-RAB3A-T86E
206149PGK EGFP-RAB3A-T86APGK EGFP-RAB3A-T86A
206150CMV HA-MADDCMV HA-MADD
206151CMV HA-RIM2CMV HA-RIM2
206152CMV SNAP-SynapsinCMV SNAP-Synapsin
206153pBI-BFP-NL1pBI-BFP-NL1
216110PGK EGFPPGK EGFP

Antibodies from Article