The alpha2delta ligand gabapentin inhibits the Rab11-dependent recycling of the calcium channel subunit alpha2delta-2.
Tran-Van-Minh A, Dolphin AC
J Neurosci. 2010 Sep 22;30(38):12856-67. doi: 10.1523/JNEUROSCI.2700-10.2010.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 206079 | EGFP Rab11a WT pcDNA3.1 Zeo (+) | Rab11a belongs to the Rab family of small GTPases, Rab11 proteins are particularly involved in trafficking through recycling endosomes |
| 206080 | EGFP Rab11a S25N pcDNA3.1 Zeo (+) | dominant-negative Rab11a mutant - S25N mutation causes inhibition of Rab11a-dependent recycling |