Beta-subunits promote the expression of Ca(V)2.2 channels by reducing their proteasomal degradation.
Waithe D, Ferron L, Page KM, Chaggar K, Dolphin AC
J Biol Chem. 2011 Mar 18;286(11):9598-611. doi: 10.1074/jbc.M110.195909. Epub 2011 Jan 13.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 206071 | Cav2.2 HA W391A pcDNA3 | expression of rabbit Cav2.2 calcium channel with an exofacial double HA tag in domain II and a mutation (W391A) in the ?1-interacting domain (AID) in the I-II loop of Cav2.2 |
| 206084 | GFP Cav2.2 W391A pRK5 | expression of rabbit Cav2.2 calcium channel with a N-terminal GFP tag and a mutation (W391A) in the ?1-interacting domain (AID) in the I-II loop of Cav2.2 that prevents Beta subunit binding |