Covalent PARylation of DNA base excision repair proteins regulates DNA demethylation.
Schwarz SD, Xu J, Gunasekera K, Schurmann D, Vagbo CB, Ferrari E, Slupphaug G, Hottiger MO, Schar P, Steinacher R
Nat Commun. 2024 Jan 2;15(1):184. doi: 10.1038/s41467-023-44209-8.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 206032 | pCAIP-hXRCC1wt-eGFP | Mammalian expression of hXRCC1wt coupled to eGFP under the control of a CAG promoter |
| 206033 | pCAIP-hXRCC1pd-eGFP | Mammalian expression of PAR-deficient hXRCC1pd coupled to eGFP under the control of a CAG promoter |
| 206035 | pEF1a-mXRCC1pd-eGFP | Mammalian expression of PAR-deficient mXRCC1pd coupled to eGFP under the control of a EF1a promoter |
| 206036 | pET28-hXRCC1pd-HIS | Bacterial expression of PAR-deficient hXRCC1pd with 6xHis tag, under the control of T7 promoter |