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An improved reporter identifies ruxolitinib as a potent and cardioprotective CaMKII inhibitor.

Reyes Gaido OE, Pavlaki N, Granger JM, Mesubi OO, Liu B, Lin BL, Long A, Walker D, Mayourian J, Schole KL, Terrillion CE, Nkashama LJ, Hulsurkar MM, Dorn LE, Ferrero KM, Huganir RL, Muller FU, Wehrens XHT, Liu JO, Luczak ED, Bezzerides VJ, Anderson ME
Sci Transl Med. 2023 Jun 21;15(701):eabq7839. doi: 10.1126/scitranslmed.abq7839. Epub 2023 Jun 21. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
205315CaMKARFluorescent Reporter for CaMKII Activity

Antibodies from Article