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Fine-tuning GPCR-mediated neuromodulation by biasing signaling through different G protein subunits.

Park JC, Luebbers A, Dao M, Semeano A, Nguyen AM, Papakonstantinou MP, Broselid S, Yano H, Martemyanov KA, Garcia-Marcos M
Mol Cell. 2023 Jul 20;83(14):2540-2558.e12. doi: 10.1016/j.molcel.2023.06.006. Epub 2023 Jun 29. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
204844pLIC-GST-GINIPExpress GST tagged-GINIP in bacterial cells for protein purification
204845p3xFLAG-CMV14-GINIPExpress 3x FLAG tagged-GINIP in mammalian cells
204846pLenti-hSynapsin-Nluc-EPAC-VVProduce lentivirus encoding Nluc-EPAC sensor in neuronal cell type
204847pLIC-His-RGS4Express His tagged-RGS4 in bacterial cells for protein purification

Antibodies from Article