Adenine transversion editors enable precise, efficient A*T-to-C*G base editing in mammalian cells and embryos.
Chen L, Hong M, Luan C, Gao H, Ru G, Guo X, Zhang D, Zhang S, Li C, Wu J, Randolph PB, Sousa AA, Qu C, Zhu Y, Guan Y, Wang L, Liu M, Feng B, Song G, Liu DR, Li D
Nat Biotechnol. 2023 Jun 15. doi: 10.1038/s41587-023-01821-9. PubMed Article
Chen L, Hong M, Luan C, Gao H, Ru G, Guo X, Zhang D, Zhang S, Li C, Wu J, Randolph PB, Sousa AA, Qu C, Zhu Y, Guan Y, Wang L, Liu M, Feng B, Song G, Liu DR, Li D
Nat Biotechnol. 2023 Jun 15. doi: 10.1038/s41587-023-01821-9. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 204605 | AXBE | Mammalian expression of adenine transversion base editor AXBE |
| 204606 | AXBEv2 | Mammalian expression of evolved adenine transversion base editor AXBEv2 |
| 204607 | ACBE | Mammalian expression of adenine-to-cytosine base editor ACBE |
| 204608 | ACBE-Q | Mammalian expression of high-accuracy adenine-to-cytosine base editor ACBE-Q |