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OPA1 helical structures give perspective to mitochondrial dysfunction.

Nyenhuis SB, Wu X, Strub MP, Yim YI, Stanton AE, Baena V, Syed ZA, Canagarajah B, Hammer JA, Hinshaw JE
Nature. 2023 Aug 23. doi: 10.1038/s41586-023-06462-1. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
204427wt Opa1Mammalian expression plasmid of GFP-tagged hOpa1 isoform 1 protein.
204428Interface-1 (a)Mammalian expression plasmid of GFP-tagged hOpa1 isoform 1 mutant protein.
204429Interface-1 (b)Mammalian expression plasmid of GFP-tagged hOpa1 isoform 1 mutant protein.
204430Interface-1 (c) Mammalian expression plasmid of GFP-tagged hOpa1 isoform 1 mutant protein.
204431Interface-1 (d) Mammalian expression plasmid of GFP-tagged hOpa1 isoform 1 mutant protein.
204432Interface-1 (e) Mammalian expression plasmid of GFP-tagged hOpa1 isoform 1 mutant protein.
204433Interface-2Mammalian expression plasmid of GFP-tagged hOpa1 isoform 1 mutant protein.
204434Palpha6 and Interface-4 (a)Mammalian expression plasmid of GFP-tagged hOpa1 isoform 1 mutant protein.
204435Interface-4 (b)Mammalian expression plasmid of GFP-tagged hOpa1 isoform 1 mutant protein.
204436Interface-5Mammalian expression plasmid of GFP-tagged hOpa1 isoform 1 mutant protein.
204437Interface-6Mammalian expression plasmid of GFP-tagged hOpa1 isoform 1 mutant protein.
204438Interface-7Mammalian expression plasmid of GFP-tagged hOpa1 isoform 1 mutant protein.
204439Interface-8Mammalian expression plasmid of GFP-tagged hOpa1 isoform 1 mutant protein.
204440Interface-9Mammalian expression plasmid of GFP-tagged hOpa1 isoform 1 mutant protein.
204441Palpha2Mammalian expression plasmid of GFP-tagged hOpa1 isoform 1 mutant protein.
204442Control-1Mammalian expression plasmid of GFP-tagged hOpa1 isoform 1 mutant protein.
204443Control-2Mammalian expression plasmid of GFP-tagged hOpa1 isoform 1 mutant protein.
204444Control-3Mammalian expression plasmid of GFP-tagged hOpa1 isoform 1 mutant protein.
204445Control-4Mammalian expression plasmid of GFP-tagged hOpa1 isoform 1 mutant protein.

Antibodies from Article