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Organoid modeling of human fetal lung alveolar development reveals mechanisms of cell fate patterning and neonatal respiratory disease.

Lim K, Donovan APA, Tang W, Sun D, He P, Pett JP, Teichmann SA, Marioni JC, Meyer KB, Brand AH, Rawlins EL
Cell Stem Cell. 2023 Jan 5;30(1):20-37.e9. doi: 10.1016/j.stem.2022.11.013. Epub 2022 Dec 8. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
204188pLenti-tetON-NOTUM-EF1a-TagRFP-2A-tet3GDoxycycline inducible lentiviral vector for human NOTUM overexpression
204189pLenti-tetON-GATA6-EF1a-TagRFP-2A-tet3GDoxycycline inducible lentiviral vector for human GATA6 overexpression
204190pLenti-tetON-TFAP2C-EF1a-TagRFP-2A-tet3GDoxycycline inducible lentiviral vector for human TFAP2C overexpression
204191pLenti-tetON-NKX2-1-R162del-EF1a-TagRFP-2A-tet3GDoxycycline inducible lentiviral vector for human NKX2-1 (R162del) overexpression
204210pLenti-tetON-NKX2-1-R178∗-EF1a-TagRFP-2A-tet3GDoxycycline inducible lentiviral vector for human NKX2-1 (R178∗) overexpression
204211pLenti-tetON-NKX2-1-Q175∗-EF1a-TagRFP-2A-tet3GDoxycycline inducible lentiviral vector for human NKX2-1 (Q175∗) overexpression
204212pLenti-tetON-NKX2-1-I207F -EF1a-TagRFP-2A-tet3GDoxycycline inducible lentiviral vector for human NKX2-1 (I207F) overexpression
204213pLenti-tetON-NKX2-1-I207M -EF1a-TagRFP-2A-tet3GDoxycycline inducible lentiviral vector for human NKX2-1 (I207M) overexpression
204214pLenti-tetON-NKX2-1(delDBD)-EF1a-TagRFP-2A-tet3GDoxycycline inducible lentiviral vector for human NKX2-1 (delDBD) overexpression

Antibodies from Article