rAAV-PHP.B escapes the mouse eye and causes lethality whereas rAAV9 can transduce aniridic corneal limbal stem cells without lethality.
Mirjalili Mohanna SZ, Korecki AJ, Simpson EM
Gene Ther. 2023 Apr 19. doi: 10.1038/s41434-023-00400-6.
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PubMed
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 49143 | pEMS2118 | AAV plasmid with smCBA promoter driving expression of iCre. Contains WPRE. |